Candida is a yeast-like parasitic microbe that is also considered fungus, which can sometimes cause thrush. Candida is generally found on the skin, on the genitals of humans and in the digestive tract. The yeast has no effect on those that maintain a healthy status but can really affect those who have weak immune systems due to medication, stress, disease or diet. When overgrown, the yeast paves the ways for a condition called Candidiasis. This condition however can be treated with different effective recommended drugs. Here are a few:
Nystatin is an anti-fungal medication that wars against contamination triggered by fungus. When taken by mouth, Nystatin treats yeast infections in the stomach or mouth. It does this by binding to a particular compound called Ergosterol, which can be seen on yeast cell walls.
And because oral Nystatin is not immersed through the intestines, it will not be effective tackling Candida infections that are outside the digestive tract, which does not at all bring side effects.
2. Amphotericin B
Amphotericin B has a similar structure to nystatin. It is also an oral anti-fungal suppository that is efficient in treating intestinal candida overgrowth, and it doesn’t bring unwelcome side effects due to the fact that it’s not absorbed by the bloodstream. Combining with the Ergosterol on the cell wall of yeast, Amphotericin B damages and cause potassium to leak leading to death of the cell.
In 1990, Fluconazole got approval from the Food and Drug Administration (FDA) making it a more recent anti-fungal drug. As a systemic anti-fungal, it is absorbed through the intestines after oral management. With low frequency of side effects that include abdominal discomfort and nausea, it is one of the safest anti-fungal suppositories.
However, Fluconazole also has some shortcomings. The charge of this drug is usually high and there’s a 3 to 6 percent rate of medication resistance for Candida albicans. This actually means that the yeasts are forming a resistance of this drug, making it of no effect in most cases.
4. Terbinafine HCL
Approved by FDA in 1992, Terbinafine HCL is the latest anti-fungal medication. You can only get this drug as oral or a relevant ointment. Though useful in treating Candida infections, it is also commonly prescribed for treating fungal infection on the nails. Terbinafine is voluntarily immersed in the body but causes minor side effects of skin allergies, abdominal discomfort and nausea.